Int. J. Mol. Sci.
(ISSN 1422-0067,
CODEN: IJMCFK)
   Section: Bioactives and Nutraceuticals
(originally Nutraceuticals and Chemopreventives)
a section of  IJMS
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   Editorial Board    Aims and Scope    Keywords    Special issues    Published Papers


Aims and Scope

This IJMS section is about molecular sciences of foods and drinks having a medicinal effect on human health. Molecular pharmacology of isolated natural products and synthetic organic compounds is also considered. Certain small amounts of natural products in food,  mainly in phytonutrients, and beverage, etc., such as phenolics, carotenoids, vitamins, sterols, may have biological properties/bioactivities (antioxidant, antimicrobial, anticancer effects). All papers will be peer reviewed as other papers of IJMS. We publish only scientific studies including well controlled in vitro studies, animal models, epidemiological studies and/or clinical studies, and correlation of chemical composition and bioactivity.

Keywords
Topics of special interest include, but are not limited to the following:

Function as Antioxidant or Radical scavenger, Antimicrobial effect, Functional foods, phytonutrients, anticarcinogens.
Chemopreventives: Carveol (a natural terpenoid alcohol, a potential antiangiogen), S-Allyl cysteine (a potentional cholesterol lowering agent); pharmacology studies.
Phytochemicals and brain function, Ting fission metabolites of Phytochemicals, Prevention of diabetes by Phytochemicals, Nutraceuticals, Structure-activity relationship, Tissue distribution of functional food factors, Metabolism of food factors, Enhancement factors for gastrointestinal absoprtion of Phytochemicals;

Special issues within this section :
Special Issue: Natural Compunds for the Treatment and Prevention of Metabolic Diseases Guest Editor:  Prof. Chang Won Choi Submission Deadline: 1 May 2008

Published Papers:

Open Access
Yoshinori Kadoma 1,* and Seiichiro Fujisawa 2 
Radical-scavenging Activity of Estrogen and Estrogen-like Compounds Using the Induction Period Method
Int. J. Mol. Sci. 2007, 8, 295-303 (PDF format, 81 K)

Open Access
Stavros Lalas 1,*, Olga Gortzi 1, John Tsaknis 2 and Konstantinos Sflomos 2

Irradiation Effect on Oxidative Condition and Tocopherol Content of Vegetable Oils
Int. J. Mol. Sci. 2007, 8, 533-540 (PDF format, 54 K)

Open Access
Dubravka Štajner 1,*, Mirjana Milošević 2 and Boris M. Popović 1
Irradiation Effects on Phenolic Content, Lipid and Protein Oxidation and Scavenger Ability of Soybean Seeds
Int. J. Mol. Sci.  2007, 8, 618-627 (PDF format, 76.3 K)

Open Access
Han-Sun Chiang 1, Wen-Bin Wu 1, Jia-You Fang 2, Bing-Huei Chen 3, Tsai-Hua Kao 3, Ying-Ting Chen 1, Chieh-Chen Huang 4 and Chi-Feng Hung 1,*
The UVB-protective effects of isoflavone extracts from soybean cake in human keratinocytes
Int. J. Mol. Sci.  2007, 8, 651-661 (PDF format, 403 K)

Open Access
Qiong Wu 1, Cheng Zheng 2,*, Zheng-Xiang Ning 1, Bao Yang 3
Modification of Low Molecular Weight Polysaccharides from Tremella Fuciformis and Their Antioxidant Activity in Vitro
Int. J. Mol. Sci.  2007, 8, 670-679 (PDF format, 85.7 K)

Open Access
Chrysoula Spanou 1, Stella Manta 2, Dimitri Komiotis 2, Albiona Dervishi 1 and Demetrios Kouretas 1,*
Antioxidant Activity of a Series of Fluorinated Pyrano-nucleoside Analogues of N4-benzoyl Cytosine and N6-benzoyl Adenine
Int. J. Mol. Sci. 2007, 8, 695-704 (PDF format, 89.4 K)

Open Access
Jan Muselík 1, María García-Alonso 2, María P. Martín-López 2, Milan Žemlička 3 and Julián C. Rivas-Gonzalo 2,*
Measurement of Antioxidant Activity of Wine Polyphenols: Catechins, Procyanidins, Anthocyanins and Pyranoanthocyanins
Int. J. Mol. Sci. 2007, 8, 797-809 (PDF format, 103 K)

Open Access
Chien-Ming Wu 1, Shu-Chun Wu 2, Wan-Jung Chung 3, Hsien-Cheng Lin 4, Kun-Tze Chen 5, Yu-Chian Chen 5, Mei-Feng Hsu 6, Jwu-Maw Yang 3, Jih-Pyang Wang 7 and Chun-Nan Lin 2,*
Antiplatelet Effect and Selective Binding to Cyclooxygenase (COX) by Molecular Docking Analysis of Flavonoids and Lignans
Int. J. Mol. Sci. 2007, 8, 830-841 (PDF format, 329 K)

Open Access
Barbara Ceh 1,*, Milica Kac 2, Iztok J. Košir 1 and Veronika Abram 2
1 Slovenian Institute for Hop Research and Brewing, Žalskega tabora 2, SI-3310 Žalec, Slovenia, E-mail: barbara.ceh-breznik@guest.arnes.si, E-mail: iztok-joze.kosir@guest.arnes.si
2 Chair of Chemisty, Department of Food Science and Technology,, Biotechnical Faculty, University of Ljubljana, Jamnikarjeva 101, SI-1111 Ljubljana, Slovenia, E-mail: milica.kac@bf.uni-lj.si, E-mail: veronika.abram@bf.uni-lj.si
* Author to whom correspondence should be addressed; Slovenian Institute for Hop Research and Brewing, Žalskega tabora 2, SI-3310 Žalec, Slovenia; E-mail: barbara.ceh-breznik@guest.arnes.si
Received:30 May 2007; in revised form: 20 August 2007 / Accepted: 6 September 2007 /  Published: 11 September 2007
Full Research Paper: Xanthohumol and Polyphenol Content in Hop Leaves and Hop Cones as to Water Supply and Cultivar
Int. J. Mol. Sci. 2007, 8, 989-1000 (PDF format, 176K)

  
Open Access
Zhiqi Shi 1,2,#,*, Fei Wang 2,#, Wei Zhou 2, Peng Zhang 3 and Yong Jian Fan 1
1 Department of Plant Protection of Nanjing Agricultural University, Nanjing210095, China; E-mail: shizhiqi@jaas.ac.cn; yjfan@jaas.ac.cn
2 Food Safety institute, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, China; E-mail: zhmdwf@jaas.cn.cn; zhouw811@jaas.ac.cn; shizhiqi@jaas.ac.cn
3 Institute of Biotechnology, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, China; E-mail: jszhangpeng@jaas.ac.cn
* Author to whom correspondence should be addressed; Tel.: +86-025-84391863; Fax: +86-025-84391260; E-mail: shizhiqi@jaas.ac.cn;
# Both Authors contributed equally to this work.
Received: 8 August 2007; in revised form: 3 September 2007 / Accepted: 6 September 2007 /  Published: 14 September 2007
Full Research Paper: Application of Osthol Induces Resistant Response in Pumpkin Leaves Against Powdery Mildew
Int. J. Mol. Sci. 2007, 8, 1001-1012 (PDF format, 332K)


Open Access
Gordana S. Ćetković, Jasna M. Čanadanović-Brunet, Sonja M. Djilas *, Vesna T. Tumbas, Siniša L. Markov and Dragoljub D. Cvetković
University of Novi Sad, Faculty of Technology, Bulevar Cara Lazara 1, 21000 Novi Sad, Serbia
* Author to whom correspondence should be addressed; E-mail: sdjilas@tehnol.ns.ac.yu
Received: 16 August 2007; in revised form: 19 September 2007 / Accepted: 20 September 2007  / Published: 29 September 2007
Full Research Paper: Antioxidant Potential, Lipid Peroxidation Inhibition and Antimicrobial Activities of Satureja montana L. subsp. kitaibelii Extracts
Int. J. Mol. Sci. 2007, 8, 1013-1027 (PDF format, 1390K)


Open Access
Péter Avar 1, Martin S. Pour Nikfardjam 2, Sándor Kunsági-Máté 3, Gergely Montskó 1, Zoltán Szabó 1, Katalin Böddi 1, Róbert Ohmacht 1 and László Márk 1,*
1 University of Pécs, Department of Biochemistry and Medical Chemistry, Szigeti u. 12, H-7624 Pécs, Hungary
2 State Research Institute for Viticulture and Pomiculture, Traubenplatz 5, D-74189, Weinsberg, Germany
3 University of Pécs, Department of General and Physical Chemistry, University of Pécs, Ifjúság 6, Pécs H-7624, Hungary
* Author to whom correspondence should be addressed; E-mail: laszlo.mark@aok.pte.hu
Received: 6 June 2007; in revised form: 13 September 2007 / Accepted: 14 September 2007  / Published: 29 September 2007
Full Research Paper:
Investigation of Phenolic Components of Hungarian Wines
Int. J. Mol. Sci. 2007, 8, 1028-1038 (PDF format, 63K)

Open Access
Xinguo Su 1, Jun Duan 1, Yueming Jiang 1, Xuewu Duan 1,* and Feng Chen 2
1 South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650; P. R. China; E-mail: jssxg@yahoo.com.cn
2 Department of Food Science & Human Nutrition, Clemson University, SC 29634, USA
* Author to whom correspondence should be addressed; Email: xwduan@scbg.ac.cn; Tel.: +86 20 37252525 Fax: +86 20 37252831

Received: 15 October 2007; in revised form: 16 November 2007 / Accepted 19 November 2007 /  Published: 29 November 2007
Full Research Paper: Polyphenolic Profile and Antioxidant Activities of Oolong Tea Infusion under Various Steeping Conditions
Int. J. Mol. Sci. 2007, 81196-1205 (PDF format, 137K)

Open Access
Zhiqi Shi *, Shouguo Shen, Wei Zhou, Fei Wang and Yongjian Fan
Food Safety Research and Service institute, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, P.R. China; E-mails: chenhao@jaas.ac.cn; zhouwei@jaas.ac.cn; lyq@jaas.ac.cn;
wangcm@jaas.ac.cn
*Author to whom correspondence should be addressed; Tel. +86-25-84391863; Fax:+ 86-25-84391260; E-mail: shizhiqi@jaas.ac.cn
Received: 13 September 2007; in revised form: 28 February 2008 / Accepted: 12 March 2008 / Published: 14 March 2008

Full Research Paper: Fusarium Graminearum Growth Inhibition Due to Glucose Starvation Caused by Osthol
Int. J. Mol. Sci. 2008, 9, 371-382 (PDF format, 972K)

Last change: 15 March 2008